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pentobarbital will lower the extent or influence of rolapitant by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Stay away from or Use Alternate Drug. Long-phrase coadministration of solid CYP3A4 inducers with rolapitant may well noticeably lessen rolapitant efficacy.pentobarbital will lessen the level or impact of acalabrutinib by affectin